Is San Francisco a Good Starting Point?
Absolutely. San Francisco is surrounded by diverse landscapes in every direction, making it one of the best hubs for designing a flexible West Coast itinerary. You can chase the coast, head inland for mountains and national parks, or combine both into a loop.
One major reason people start their West Coast road trip here is access to the Pacific Coast Highway (Highway 1). This is the scenic route that runs from Northern California down to Southern California - famous for dramatic cliffs, ocean viewpoints, and towns worth lingering in. From San Francisco, the PCH begins almost immediately once you drive south; you don’t have to wait hours to reach the “pretty part.”
And you’re not limited to self-driving. Many visitors choose:
Guided tours from companies leaving directly from San Francisco (ideal if you don’t want to deal with rental cars or parking). You can explore options such as USA West tours departing from SFO, which cover major highlights including Yosemite, Las Vegas, the Grand Canyon, and the coastal cities.
Public transit + local tours for partial explorations - perfect for travelers who want to see places like Santa Cruz, Monterey, or wine country without a long road trip.
Self-drive road trips (the most flexible choice) where you control the pace, viewpoints, and stops.
No matter which style you choose, starting from San Francisco gives you a head start on scenery.
How Long Should You Take for a West Coast Trip?
A compressed version is possible, but covering the West Coast comfortably usually takes more than a long weekend. Distances stretch fast - especially once you go beyond the Bay Area and dive into Los Angeles, San Diego, or national parks further inland.
Here’s a quick guide based on typical visitor patterns:
3-5 days - Good for local highlights: Monterey, Carmel, Big Sur, Napa Valley, and Yosemite (one major point + one minor point). These are popular picks for short organized tours such as short West Coast packages from SFO.
7 days - Enough time for a compact West Coast road trip from San Francisco that includes Monterey, Big Sur, Santa Barbara, LA, and San Diego.
10-12 days - Ideal for combining the Pacific Coast Highway with national parks like Yosemite or Sequoia, or extending from LA to Las Vegas and the Grand Canyon.
14 days or more - You can complete a full coast-to-desert loop or even go north toward Oregon and Washington for a broader West Coast itinerary
Most travelers aim for 7-14 days. That’s the sweet spot where the pace feels reasonable and you can balance cities with nature without rushing.
Best USA West Destinations to Visit from SFO
Planning a West Coast vacation isn’t just about choosing the big names - it’s about mixing cities, coastline, vineyards, and parks so the journey stays interesting day after day. Here are some of the most popular places to include when starting from SFO:
1. Monterey & Carmel-by-the-Sea
Just two hours south of San Francisco, these towns are among the easiest coastal highlights to reach. Popular stops include Cannery Row, the Monterey Bay Aquarium, and the famous 17-Mile Drive.
2. Big Sur
The ultimate Highway 1 destination. Expect cliffside pullouts, waterfalls, and rugged beaches. It’s often considered the most scenic stretch of the Pacific Coast Highway.
3. Santa Barbara
A clean, polished seaside city with palm-lined beaches and Spanish-style architecture. Many travelers use it as a rest stop on the way to Los Angeles.
4. Los Angeles
The sprawling entertainment capital with neighborhoods that feel like mini-cities of their own. From Hollywood Boulevard to Santa Monica Pier, it’s easy to get stuck here longer than expected.
5. San Diego
If your West Coast road trip from San Francisco continues all the way down, San Diego is a favorite final stop. Warm weather, laid-back beaches, and excellent food make it ideal for ending the journey on a relaxing note.
6. Yosemite National Park
If your plan includes nature, Yosemite is one of the West’s most iconic landscapes - waterfalls in spring, granite cliffs all year, and excellent hiking from easy loops to challenging climbs.
7. Las Vegas & the Grand Canyon
Many guided USA West tours from San Francisco include a detour to the Southwest, connecting California’s coastline with deserts, canyons, and neon lights.
West Coast Itineraries from San Francisco
Below are practical examples for your reference.
1-Week Itinerary: Classic Coastline
Day 1: San Francisco → Monterey (via Highway 1)
Day 2: Monterey → Carmel → Big Sur
Day 3: Big Sur → San Simeon → Santa Barbara
Day 4-5: Santa Barbara → Los Angeles (Hollywood, Santa Monica)
Day 6-7: Los Angeles → San Diego → return
This route hits the highlights and follows the coastline almost the entire way. It’s ideal for first-time visitors and pairs well with guided tour segments.
10-Day Itinerary: Coast + National Parks Combo
Day 1-2: San Francisco
Day 3: Monterey & Carmel
Day 4: Big Sur
Day 5: Santa Barbara
Day 6-7: Los Angeles
Day 8-9: Drive inland to Yosemite (or Sequoia)
Day 10: Return to SFO
This works well if you want both the coast and the famous national parks without going too far east.
2-Week Itinerary: Full West Coast + Southwest Loop
Day 1-2: San Francisco sightseeing
Day 3-5: Monterey → Big Sur → Santa Barbara
Day 6-7: Los Angeles
Day 8-9: San Diego
Day 10: Fly or drive to Las Vegas
Day 11-12: Grand Canyon (South Rim or West Rim)
Day 13-14: Yosemite or Lake Tahoe on the return
This itinerary mimics many structured West Coast tours from San Francisco but with more flexibility to personalize your pace and choice of destinations.
Pro Tips for a Smooth West Coast Trip
Weather varies more than you might expect
California’s coastal weather is mild year-round, but fog along Highway 1 (especially around Big Sur) is common in summer mornings. Spring and fall often deliver clearer views.
Book key attractions ahead of time
Places like Yosemite Valley, Hearst Castle, or special timed-entry viewpoints get busy. Reserve parking or entrance passes early, especially in peak months.
Driving times are longer than Google Maps suggests
Highway 1 is slow on purpose - sharp turns, narrow sections, and lots of scenic pullouts. Plan shorter daily distances than you would on regular highways.
Watch for road closures
Highway 1 occasionally experiences slides, especially around Big Sur. Check updated conditions via official Caltrans reports or park websites before you leave.
Don’t underestimate the sun
Even when it's cool or foggy, UV can be em along the coast and in higher elevations like Yosemite or Lake Tahoe. Sunscreen and water are essential.
Parking in cities can be tricky
In San Francisco, Los Angeles, and San Diego, consider park-and-ride options, rideshares, or public transit when practical. It reduces stress and saves time.
Tours can be a helpful alternative
If you’re not confident navigating mountain roads or long coastal stretches, consider joining structured experiences such as guided West Coast tours departing from San Francisco. They’re especially convenient for Yosemite, Los Angeles, or multi-day Southwest routes.